"We are in the midst of a revolution in the application of SAXS
to the analysis of large molecular complexes”
- Nagar and Kuriyan (Structure 2005)
~ March 21-23, 2013 ~
BioSAXS is a solution-based x-ray scattering technique that can yield valuable structural information on biomolecules such as the size, low-resolution shape, degree of folding, and oligomeric state.
This practical course for molecular biologists will focus on collecting, processing, and publishing BioSAXS data.
No previous x-ray experience necessary.
Students will have the opportunity to collect data on CHESS beamlines using protein standards and/or their own samples.
Processing software, installation help, and tutorials will be provided.
Cost: $250 academic; $350 industrial
basic principles and processing methods
critical sample preparation tips
evaluating data quality
computing envelopes and data modeling
overview of advanced and emerging methods
what you need to know for publication
Lecturers: R. Gillilan (MacCHESS), S. Nielsen (Danish Technical University), K. Gupta (UPENN Medical School), T. Grant (HWI), and N. Ando (MIT)