ACETONE
MSDS Number: A0446 --- Effective Date: 04/10/01
1. Product Identification
Synonyms: Dimethylketone; 2-propanone; dimethylketal
CAS No.: 67-64-1
Molecular Weight: 58.08
Chemical Formula: (CH3)2CO
Product Codes:
J.T. Baker: 5356, 5580, 5805, 9001, 9002, 9003, 9004, 9005, 9006, 9007, 9008,
9009, 9010, 9015, 9036, 9125, 9254, 9271, A134, V655
Mallinckrodt: 0018, 2432, 2435, 2437, 2438, 2440, 2443, 2445, 2850, H451,
H580, H981
2. Composition/Information on Ingredients
Ingredient CAS No Percent Hazardous
--------------------------------------- ------------ ------- ---------
Acetone 67-64-1 99 - 100% Yes
3. Hazards Identification
Emergency Overview
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DANGER! EXTREMELY FLAMMABLE LIQUID AND VAPOR. VAPOR MAY CAUSE FLASH FIRE.
HARMFUL IF SWALLOWED OR INHALED. CAUSES IRRITATION TO SKIN, EYES AND
RESPIRATORY TRACT. AFFECTS CENTRAL NERVOUS SYSTEM.
J.T. Baker SAF-T-DATA(tm) Ratings (Provided here for your
convenience)
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Health Rating: 1 - Slight
Flammability Rating: 4 - Extreme (Flammable)
Reactivity Rating: 2 - Moderate
Contact Rating: 1 - Slight
Lab Protective Equip: GOGGLES; LAB COAT; VENT HOOD; PROPER GLOVES; CLASS B
EXTINGUISHER
Storage Color Code: Red (Flammable)
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Potential Health Effects
----------------------------------
Inhalation:
Inhalation of vapors irritates the respiratory tract. May cause coughing,
dizziness, dullness, and headache. Higher concentrations can produce central
nervous system depression, narcosis, and unconsciousness.
Ingestion:
Swallowing small amounts is not likely to produce harmful effects. Ingestion
of larger amounts may produce abdominal pain, nausea and vomiting. Aspiration
into lungs can produce severe lung damage and is a medical emergency. Other
symptoms are expected to parallel inhalation.
Skin Contact:
Irritating due to defatting action on skin. Causes redness, pain, drying and
cracking of the skin.
Eye Contact:
Vapors are irritating to the eyes. Splashes may cause severe irritation, with
stinging, tearing, redness and pain.
Chronic Exposure:
Prolonged or repeated skin contact may produce severe irritation or
dermatitis.
Aggravation of Pre-existing Conditions:
Use of alcoholic beverages enhances toxic effects. Exposure may increase the
toxic potential of chlorinated hydrocarbons, such as chloroform,
trichloroethane.
4. First Aid Measures
Inhalation:
Remove to fresh air. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Get medical attention.
Ingestion:
Aspiration hazard. If swallowed, vomiting may occur spontaneously, but DO NOT
INDUCE. If vomiting occurs, keep head below hips to prevent aspiration into
lungs. Never give anything by mouth to an unconscious person. Call a physician
immediately.
Skin Contact:
Immediately flush skin with plenty of water for at least 15 minutes. Remove
contaminated clothing and shoes. Get medical attention. Wash clothing before
reuse. Thoroughly clean shoes before reuse.
Eye Contact:
Immediately flush eyes with plenty of water for at least 15 minutes, lifting
upper and lower eyelids occasionally. Get medical attention.
5. Fire Fighting Measures
Fire:
Flash point: -20C (-4F) CC
Autoignition temperature: 465C (869F)
Flammable limits in air % by volume:
lel: 2.5; uel: 12.8
Extremely Flammable Liquid and Vapor! Vapor may cause flash fire.
Explosion:
Above flash point, vapor-air mixtures are explosive within flammable limits
noted above. Vapors can flow along surfaces to distant ignition source and
flash back. Contact with strong oxidizers may cause fire. Sealed containers
may rupture when heated. This material may produce a floating fire hazard.
Sensitive to static discharge.
Fire Extinguishing Media:
Dry chemical, alcohol foam or carbon dioxide. Water may be ineffective. Water
spray may be used to keep fire exposed containers cool, dilute spills to
nonflammable mixtures, protect personnel attempting to stop leak and disperse
vapors.
Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved
self-contained breathing apparatus with full facepiece operated in the
pressure demand or other positive pressure mode.
6. Accidental Release Measures
Ventilate area of leak or spill. Remove all sources of ignition. Wear
appropriate personal protective equipment as specified in Section 8. Isolate
hazard area. Keep unnecessary and unprotected personnel from entering. Contain
and recover liquid when possible. Use non-sparking tools and equipment.
Collect liquid in an appropriate container or absorb with an inert material
(e. g., vermiculite, dry sand, earth), and place in a chemical waste
container. Do not use combustible materials, such as saw dust. Do not flush to
sewer! If a leak or spill has not ignited, use water spray to disperse the
vapors, to protect personnel attempting to stop leak, and to flush spills away
from exposures. US Regulations (CERCLA) require reporting spills and releases
to soil, water and air in excess of reportable quantities. The toll free
number for the US Coast Guard National Response Center is (800) 424-8802.
J. T. Baker SOLUSORB(R) solvent adsorbent is recommended for spills of this
product.
7. Handling and Storage
Protect against physical damage. Store in a cool, dry well-ventilated
location, away from any area where the fire hazard may be acute. Outside or
detached storage is preferred. Separate from incompatibles. Containers should
be bonded and grounded for transfers to avoid static sparks. Storage and use
areas should be No Smoking areas. Use non-sparking type tools and equipment,
including explosion proof ventilation. Containers of this material may be
hazardous when empty since they retain product residues (vapors, liquid);
observe all warnings and precautions listed for the product.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits:
Acetone:
-OSHA Permissible Exposure Limit (PEL):
1000 ppm (TWA)
-ACGIH Threshold Limit Value (TLV):
500 ppm (TWA), 750 ppm (STEL) A4 - not classifiable as a human carcinogen
Ventilation System:
A system of local and/or general exhaust is recommended to keep employee
exposures below the Airborne Exposure Limits. Local exhaust ventilation is
generally preferred because it can control the emissions of the contaminant at
its source, preventing dispersion of it into the general work area. Please
refer to the ACGIH document, Industrial Ventilation, A Manual of
Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved):
If the exposure limit is exceeded, a half-face organic vapor respirator may be
worn for up to ten times the exposure limit or the maximum use concentration
specified by the appropriate regulatory agency or respirator supplier,
whichever is lowest. A full-face piece organic vapor respirator may be worn up
to 50 times the exposure limit or the maximum use concentration specified by
the appropriate regulatory agency or respirator supplier, whichever is lowest.
For emergencies or instances where the exposure levels are not known, use a
full-face piece positive-pressure, air-supplied respirator. WARNING:
Air-purifying respirators do not protect workers in oxygen-deficient
atmospheres.
Skin Protection:
Wear impervious protective clothing, including boots, gloves, lab coat, apron
or coveralls, as appropriate, to prevent skin contact.
Eye Protection:
Use chemical safety goggles and/or a full face shield where splashing is
possible. Maintain eye wash fountain and quick-drench facilities in work area.
9. Physical and Chemical Properties
Appearance:
Clear, colorless, volatile liquid.
Odor:
Fragrant, mint-like
Solubility:
Miscible in all proportions in water.
Specific Gravity:
0.79 @ 20C/4C
pH:
No information found.
% Volatiles by volume @ 21C (70F):
100
Boiling Point:
56.5C (133F) @ 760 mm Hg
Melting Point:
-95C (-139F)
Vapor Density (Air=1):
2.0
Vapor Pressure (mm Hg):
400 @ 39.5C (104F)
Evaporation Rate (BuAc=1):
ca. 7.7
10. Stability and Reactivity
Stability:
Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products:
Carbon dioxide and carbon monoxide may form when heated to decomposition.
Hazardous Polymerization:
Will not occur.
Incompatibilities:
Concentrated nitric and sulfuric acid mixtures, oxidizing materials,
chloroform, alkalis, chlorine compounds, acids, potassium t-butoxide.
Conditions to Avoid:
Heat, flames, ignition sources and incompatibles.
11. Toxicological Information
Oral rat LD50: 5800 mg/kg; Inhalation rat LC50: 50,100mg/m3; Irritation eye
rabbit, Standard Draize, 20 mg severe; investigated as a tumorigen, mutagen,
reproductive effector.
--------\Cancer Lists\------------------------------------------------------
---NTP Carcinogen---
Ingredient Known Anticipated IARC Category
------------------------------------ ----- ----------- -------------
Acetone (67-64-1) No No None
12. Ecological Information
Environmental Fate:
When released into the soil, this material is expected to readily biodegrade.
When released into the soil, this material is expected to leach into
groundwater. When released into the soil, this material is expected to quickly
evaporate. When released into water, this material is expected to readily
biodegrade. When released to water, this material is expected to quickly
evaporate. This material has a log octanol-water partition coefficient of less
than 3.0. This material is not expected to significantly bioaccumulate. When
released into the air, this material may be moderately degraded by reaction
with photochemically produced hydroxyl radicals. When released into the air,
this material may be moderately degraded by photolysis. When released into the
air, this material is expected to be readily removed from the atmosphere by
wet deposition.
Environmental Toxicity:
This material is not expected to be toxic to aquatic life. The LC50/96-hour
values for fish are over 100 mg/l.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be handled as
hazardous waste and sent to a RCRA approved incinerator or disposed in a RCRA
approved waste facility. Processing, use or contamination of this product may
change the waste management options. State and local disposal regulations may
differ from federal disposal regulations. Dispose of container and unused
contents in accordance with federal, state and local requirements.
14. Transport Information
Domestic (Land, D.O.T.)
-----------------------
Proper Shipping Name: ACETONE
Hazard Class: 3
UN/NA: UN1090
Packing Group: II
Information reported for product/size: 350LB
International (Water, I.M.O.)
-----------------------------
Proper Shipping Name: ACETONE
Hazard Class: 3.1
UN/NA: UN1090
Packing Group: II
Information reported for product/size: 350LB
15. Regulatory Information
--------\Chemical Inventory Status - Part 1\---------------------------------
Ingredient TSCA EC Japan Australia
----------------------------------------------- ---- --- ----- ---------
Acetone (67-64-1) Yes Yes Yes Yes
--------\Chemical Inventory Status - Part 2\---------------------------------
--Canada--
Ingredient Korea DSL NDSL Phil.
----------------------------------------------- ----- --- ---- -----
Acetone (67-64-1) Yes Yes No Yes
--------\Federal, State & International Regulations - Part 1\----------------
-SARA 302- ------SARA 313------
Ingredient RQ TPQ List Chemical Catg.
----------------------------------------- --- ----- ---- --------------
Acetone (67-64-1) No No Yes No
--------\Federal, State & International Regulations - Part 2\----------------
-RCRA- -TSCA-
Ingredient CERCLA 261.33 8(d)
----------------------------------------- ------ ------ ------
Acetone (67-64-1) 5000 U002 No
Chemical Weapons Convention: No TSCA 12(b): Yes CDTA: Yes
SARA 311/312: Acute: Yes Chronic: No Fire: Yes Pressure: No
Reactivity: No (Pure / Liquid)
Australian Hazchem Code: 2[Y]E
Poison Schedule: No information found.
WHMIS:
This MSDS has been prepared according to the hazard criteria of the Controlled
Products Regulations (CPR) and the MSDS contains all of the information
required by the CPR.
16. Other Information
NFPA Ratings: Health: 1 Flammability: 3 Reactivity: 0
Label Hazard Warning:
DANGER! EXTREMELY FLAMMABLE LIQUID AND VAPOR. VAPOR MAY CAUSE FLASH FIRE.
HARMFUL IF SWALLOWED OR INHALED. CAUSES IRRITATION TO SKIN, EYES AND
RESPIRATORY TRACT. AFFECTS CENTRAL NERVOUS SYSTEM.
Label Precautions:
Keep away from heat, sparks and flame.
Keep container closed.
Use only with adequate ventilation.
Wash thoroughly after handling.
Avoid breathing vapor.
Avoid contact with eyes, skin and clothing.
Label First Aid:
Aspiration hazard. If swallowed, vomiting may occur spontaneously, but DO NOT
INDUCE. If vomiting occurs, keep head below hips to prevent aspiration into
lungs. Never give anything by mouth to an unconscious person. Call a physician
immediately. If inhaled, remove to fresh air. If not breathing, give
artificial respiration. If breathing is difficult, give oxygen. In case of
contact, immediately flush eyes or skin with plenty of water for at least 15
minutes. Remove contaminated clothing and shoes. Wash clothing before reuse.
In all cases, get medical attention.
Product Use:
Laboratory Reagent.
Revision Information:
No changes.
Disclaimer:
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Mallinckrodt Baker, Inc. provides the information contained herein in good
faith but makes no representation as to its comprehensiveness or accuracy.
This document is intended only as a guide to the appropriate precautionary
handling of the material by a properly trained person using this product.
Individuals receiving the information must exercise their independent judgment
in determining its appropriateness for a particular purpose. MALLINCKRODT
BAKER, INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED,
INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A
PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE
PRODUCT TO WHICH THE INFORMATION REFERS. ACCORDINGLY, MALLINCKRODT BAKER, INC.
WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF OR RELIANCE UPON
THIS INFORMATION.
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Prepared by: Environmental Health & Safety
Phone Number: (314) 654-1600 (U.S.A.)