The 2017 BioSAXS Winter Run

The Winter 2017 BioSAXS running period starts November 1 this year and runs until December 21. Be sure to reserve your beamtime as soon as possible while slots are still available. We’ve been busy with lots of improvements this Summer … you might not even recognize G1!

We have a new safety interlock system that uses a touch screen. No more keys! The new magnetic lock will automatically latch as soon as you close the door. The station control area is greatly simplified and we’ve freed up considerable desk space.

We have a brand new AKTA Pure system for use in SEC-SAXS with 3-wavelength detection, updated software, and bubble detection for improved column safety.

We will be testing our new Compound Refractive Lens (CRL) system for microfocus. We expect that microfocus beams will greatly enhance our developing time-resolved BioSAXS program by allowing us to push to smaller timescales.

Our RAW software for data processing continues to grow by leaps and bounds and is being adpoted by many other facilities worldwide. RAW is a multi-platform, free, open source package that can run efficiently on a personal laptop. The software can handle some 27 different detector image formats (including PILATUS TIFF and CBF types), and has sophisticated masking and beamstop normalization capabilities. Beyond the requisite standard plots and Guinier analysis, RAW provides 4 different types of molecular weight estimates, including built-in absolute scale. Two different indirect Fourier transform methods are implemented (GNOM and BIFT), and the user interface is seamlessly integrated with the most widely used components of the popular ATSAS suite, including DAMMIF (shape reconstruction) and the new AMBIMETER program for determining shape ambiguity. RAW also supports the collection and processing of SEC-SAXS data. We’ve made multiple new improvements including automatic profile comparisons for merging multiple exposures, advanced processing for size-exclusion chromatography, normalized Kratky plots, and much more: all carefully documented for your ease of use.

Check out our new publication on RAW:

Hopkins. J. B., Gillilan, R. E., Skou, S. “BioXTAS RAW: improvements to a free open-source program for small-angle X-ray scattering data reduction and analysis”. J. Appl. Cryst. (2017), 50. DOI: 10.1107/S1600576717011438

Full documentation, including a printable manual and YouTube videos can be found on SourceForge as well as on this website: sourceforge.net/projects/bioxtasraw.

Looking forward to seeing you all this Winter!!