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DNA to RNA - more ways than one
Information encoded in our genes controls how we live and grow. As part of this complex process, DNA is transcribed to RNA, one "letter" (nucleotide) at a time, by an enzyme called RNA polymerase (RNAP).
A pioneer of scientific tools
Sol Gruner, known for developing x-ray detectors, is a toolmaker, tackling scientific problems and exploring the unknown.
RAW Power! MacCHESS software brings synchrotron-level data processing to the laptop and home laboratory
Since its introduction by Søren Skou (Nielsen) in 2010, the BioXTAS RAW software has been a familiar interface to the many biomedical scientists collecting data at CHESS beamlines in recent years.
MacCHESS launches international data collection
MacCHESS crossed a new threshold in June 2017 with international data collection. Normand Cyr collected data at CHESS beamline F1 remotely from the D'Avanzo lab at the University of Montreal in Quebec, Canada.
Focusing on microbeam: Initial installment of CRLs at CHESS
A great challenge at many x-ray beamlines is to direct x-rays into in a very small, very clean footprint while maintaining high photon flux.
Changing the identity of cellular enzyme spawns new pathway
A previously reported method involving standard recombinant DNA techniques and some novel design principles enabled a team of Cornell chemical engineers to make large quantities of functional integral membrane proteins simply and inexpensively – all without the use of harsh chemicals or detergents, which are typically used today.
BioSAXS Essentials 7 training course now complete!
We have now completed our 7th BioSAXS Essentials training course! BioSAXS (Biological Small Angle X-ray Solution Scattering) is a highly popular technique for understanding the structure and behavior of biomolecules in solution, without the need for freezing or crystallization.
Structural insight into HIV reverse transcriptase
Eddy Arnold of Rutgers University has been studying the HIV virus for a long time. A frequent user of CHESS, Arnold has been using the technique of X-ray crystallography to investigate the structure of HIV proteins and learn more about inhibitors of those proteins which might lead to drugs to fight AIDS. His efforts have been reported here several times (1, 2).