MacCHESS (Macromolecular X-ray science at the Cornell High Energy Synchrotron Source) provides a facility where scientists can use both established and emerging technologies to pursue the goals of the biomedical research community. Work performed at MacCHESS, using tools including e.g. crystallography and small-angle X-ray scattering, yields important insights into fundamental biological processes, such as signaling across membranes, regulation of ion channels in neuronal function, enzyme catalysis, and gene expression.

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Sector 7 Beamlines:
HP BioSAXS & BioSAXS: 7A1
HPBio MX & FlexX: 7B2

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Gabrielle Illava: From SERCCS to PhD
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CHESS Research Uses Pressure To Understand RNA Dynamics
Portrait of Catherine Royer
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Summer 2023 Undergraduate Students at CHESS
REU, SERCCS, PREM and SUNRiSE students
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DAC set up

High Pressure and More

A large part of the biosphere exists under very high pressure and may have evolved there since the earliest times yet researchers have precious little structural information.
MX at MacCHESS

MX at MacCHESS

Macromolecular crystallography (MX) is a method 
for determining the structures of proteins, viruses 
and nucleic acids (RNA and DNA) from X-ray 
BioSAXS beamline

BioSAXS at MacCHESS

Biological Small Angle X-ray Solution Scattering (BioSAXS)
is a popular method that yields valuable structural
MacCHESS Publications

MacCHESS User Publications

Macchess people_crystals

MacCHESS people