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BioSAXS beam line

BioSAXS at MacCHESS

Biological Small Angle X-ray Solution Scattering (BioSAXS) informs on the size and shape of biomolecules in solution, offering valuable insights into their dynamics and behaviors under native, physiological conditions. Owing to the experimental ease and flexibility, BioSAXS has garnered numerous applications, including studies on flexibility, disorder, protein folding, conformational changes, and oligomeric states; validation of structural models; and screening sample conditions for cryo-EM and crystallography. Moreover, BioSAXS has increasingly been utilized in research on liquid-liquid phase separation (LLPS), intrinsically disordered proteins (IDPs), and lipid nanoparticles (LNPs).

Proposal Submission Information

BeamPASS

User Guide

7A1 beamline

XBio / BioSAXS beamline

BioSAXS panel

What is BioSAXS?

DENSS

Experiment types

Chemistry lab

Sector 7 chemistry lab

PCR plate

Sample mail-in and remote operation

Book

Data, processing, and other resources

Demonstration videos

Demonstration videos

BioSAXS: Acknowlegment

Publishing and acknowledging BioSAXS work

Journal

MacCHESS User Publications

Tour group

Sector 7 Virtual Tour

Crystals

People of MacCHESS

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