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Surprising mechanism of an enzyme in a membrane
Many cellular processes, particularly intercellular signaling, require enzyme-catalyzed reactions to occur inside a cell membrane.

Fluorescence imaging at the MacCHESS A1 and F1 beamlines makes crystal centering easier
Macromolecules typically produce only small crystals; to observe diffraction from them (and determine the molecular structure) we need the intense, highly collimated beam from a synchrotron source.

BioSAXS Essentials 6 workshop in May
MacCHESS is offering its sixth intensive HOWTO course in BioSAXS.

Unusually deformable protein crystals
Application of high pressure to crystals of Snf7 has an unusual effect. Cryocooling protein crystals under pressure (HPC) can reduce damage due to the cooling process.

MacCHESS runs ACA course on small angle scattering
Following the successful BioSAS training workshop held at the 2013 American Crystallographic Association annual meeting, the ACA approved a new proposal from MacCHESS for a small-angle scattering workshop bringing together experts in both biology and soft matter.

Mutations in the canine parvovirus capsid make it more infectious
Canine parvovirus (CPV) is closely related to the feline panleukopenia virus (FPV), also a parvovirus, that infects domestic cats and some non-domestic carnivores.

Users show off innovative work at BioSAXS Essentials V workshop
The Macromolecular Diffraction Facility at the Cornell High Energy Synchrotron Source (MacCHESS) held its fifth annual BioSAXS Essentials workshop on October 30 to November 1, 2014.

Fine details of transcribing DNA to RNA
RNA polymerase (RNAP) assembles an RNA strand corresponding to the DNA sequence of a gene, in a precisely choreographed series of molecular motions.